butabarbital will minimize the level or outcome of amlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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Teniposide: Barbiturates could decrease the serum focus of Teniposide. Administration: Think about solutions to combined therapy with barbiturates and teniposide as a result of possible for decreased teniposide concentrations.
butabarbital will reduce the level or outcome of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Primidone: May possibly improve the adverse/harmful effect of Barbiturates. Primidone is transformed to phenobarbital, and thus becomes additive with existing barbiturate therapy. Keep an eye on therapy
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Suitable experiments so far have not demonstrated pediatric-unique problems that would limit the usefulness of butabarbital in small children website when utilized ahead of a surgical method. Having said that, safety and efficacy have not been recognized in youngsters to treat insomnia. Geriatric
butabarbital will lessen the extent or impact of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Stay clear of coadministration of lefamulin with sturdy or average CYP3A inducers Until the advantage outweighs dangers. Watch for lessened efficacy.
butabarbital improves outcomes of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Caution/Monitor. Coadministration of ifosfamide with CYP2B6 inducers could enhance metabolism of ifosfamide to its metabolite. Keep an eye on for greater results/toxicities if coupled with CYP2B6 inducers.
butabarbital will lower the extent or influence of rabeprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.
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butabarbital will reduce the extent or effect of eplerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.
butabarbital will lower the level or result of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Reasonable CYP3A4 inducers could lessen progestin concentration; contemplate utilization of supplemental barrier procedures
butabarbital increases consequences of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. CYP3A4 inducers could enhance the metabolism of ifosfamide to its Lively alkylating metabolites.